Showing posts with label biochemical research. Show all posts
Showing posts with label biochemical research. Show all posts

August 19, 2008

History of Humans Used as Guinea Pigs by US Government and Military

This message is available online at
http://www.WantToKnow.info/humanguineapigs

Dear friends,

Below is a comprehensive list of the use of humans as guinea pigs in biological experiments. Unfortunately, there are no links to confirm the information presented presented. However, having researched this subject quite thoroughly, I can tell you that I have read about almost all of these experiments in reliable books with footnotes providing information on how to verify these facts.

The three books mentioned in the mind control section of our resources list at www.WantToKnow.info/resources#mindcontrol contain most of this information, which you can verify using the relevant footnotes.

Many in the government and military sadly feel no compulsion to inform us of when they use us in experiments. Note that a number of these experiments specifically targeted minorities and those in poor areas. By exposing this information, we can help to build the critical mass necessary to put a stop to all of this. Please help to spread the word.

With very best wishes, Fred Burks for the WantToKnow.info team

History of Experimentation on Human Guinea Pigs

1931 - Dr. Cornelius Rhoads, under the auspices of the Rockefeller Institute for Medical Investigations, infects human subjects with cancer cells. He later goes on to establish the U.S. Army Biological Warfare facilities in Maryland, Utah, and Panama, and is named to the U.S. Atomic Energy Commission. While there, he begins a series of radiation exposure experiments on American soldiers and civilian hospital patients.

1932 - The Tuskegee Syphilis Study begins. 200 black men diagnosed with syphilis are never told of their illness, are denied treatment, and instead are used as human guinea pigs in order to follow the progression and symptoms of the disease. They all subsequently die from syphilis, their families never told that they could have been treated.

1935 - The Pellagra Incident. After millions of individuals die from pellagra over a span of two decades, the U.S. Public Health Service finally acts to stem the disease. The director of the agency admits it had known for at least 20 years that Pellagra is caused by a niacin deficiency but failed to act since most of the deaths occurred within poverty-stricken black populations.

1940 - Four hundred prisoners in Chicago are infected with malaria in order to study the effects of new and experimental drugs to combat the disease. Nazi doctors later on trial at Nuremberg cite this American study to defend their own actions during the Holocaust.

1942 - Chemical Warfare Services begins mustard gas experiments on approximately 4,000 servicemen. The experiments continue until 1945 and made use of Seventh Day Adventists who chose to become human guinea pigs rather than serve on active duty.

1943 - In response to Japan's full-scale germ warfare program, the U.S. begins research on biological weapons at Fort Detrick, MD.

1944 - U.S. Navy uses human subjects to test gas masks and clothing. Individuals were locked in a gas chamber and exposed to mustard gas and lewisite.

1945 - Project Paperclip is initiated. The U.S. State Department, Army intelligence, and the CIA recruit Nazi scientists and offer them immunity and secret identities in exchange for work on top
secret government projects in the United States.

1945 - "Program F" is implemented by the U.S. Atomic Energy Commission (AEC). This is the most extensive U.S. study of the health effects of fluoride, which was the key chemical component in atomic bomb production. One of the most toxic chemicals known to man, fluoride,
it is found, causes marked adverse effects to the central nervous system but much of the information is squelched in the name of national security because of fear that lawsuits would undermine full-scale production of atomic bombs.

1946 - Patients in VA hospitals are used as guinea pigs for medical experiments. In order to allay suspicions, the order is given to change the word "experiments" to "investigations" or "observations" whenever reporting a medical study performed in one of the nation's veteran's hospitals.

1947 - Colonel E.E. Kirkpatrick of the U.S. Atomic Energy Commission issues a secret document (Document 07075001, January 8, 1947) stating that the agency will begin administering intravenous doses of radioactive substances to human subjects.

1947 - The CIA begins its study of LSD as a potential weapon for use by American intelligence. Human subjects (both civilian and military) are used with and without their knowledge.

1950 - Department of Defense begins plans to detonate nuclear weapons in desert areas and monitor downwind residents for medical problems and mortality rates.

1950 - In an experiment to determine how susceptible an American city would be to biological attack, the U.S. Navy sprays a cloud of bacteria from ships over San Francisco. Monitoring devices are situated throughout the city in order to test the extent of infection. Many residents become ill with pneumonia-like symptoms.

1951 - Department of Defense begins open air tests using disease-producing bacteria and viruses. Tests last through 1969 and there is concern that people in the surrounding areas have been exposed.

1953 - U.S. military releases clouds of zinc cadmium sulfide gas over Winnipeg, St. Louis, Minneapolis, Fort Wayne, the Monocacy River Valley in Maryland, and Leesburg, Virginia. Their intent is to determine how efficiently they could disperse chemical agents.

1953 - Joint Army-Navy-CIA experiments are conducted in which tens of thousands of people in New York and San Francisco are exposed to the airborne germs Serratia marcescens and Bacillus glogigii.

1953 - CIA initiates Project MKULTRA. This is an eleven year research program designed to produce and test drugs and biological agents that would be used for mind control and behavior modification. Six of the subprojects involved testing the agents on unwitting human beings.

1955 - The CIA, in an experiment to test its ability to infect human populations with biological agents, releases a bacteria withdrawn from the Army's biological warfare arsenal over Tampa Bay, Fl.

1956 - U.S. military releases mosquitoes infected with yellow fever over Savannah, Ga and Avon Park, Fl. Following each test, Army agents posing as public health officials test victims for effects.

1960 - The Army Assistant Chief-of-Staff for Intelligence (ACSI) authorizes field testing of LSD in Europe and the Far East. Testing of the European population is code named Project THIRD CHANCE; testing of the Asian population is code named Project DERBY HAT.

1965 - Project CIA and Department of Defense begin Project MKSEARCH, a program to develop a capability to manipulate human behavior through the use of mind-altering drugs.

1965 - Prisoners at the Holmesburg State Prison in Philadelphia are subjected to dioxin, the highly toxic chemical component of Agent Orange used in Viet Nam. The men are later studied for development of cancer, which indicates that Agent Orange had been a suspected carcinogen all along.

1966 - CIA initiates Project MKOFTEN, a program to test the toxicological effects of certain drugs on humans and animals.

1966 - U.S. Army dispenses Bacillus subtilis variant niger throughout the New York City subway system. More than a million civilians are exposed when army scientists drop lightbulbs filled with the bacteria onto ventilation grates.

1967 - CIA and Department of Defense implement Project MKNAOMI, successor to MKULTRA and designed to maintain, stockpile and test biological and chemical weapons.

1968 - CIA experiments with the possibility of poisoning drinking water by injecting chemicals into the water supply of the FDA in Washington, D.C.

1969 - Dr. Robert MacMahan of the Department of Defense requests from congress $10 million to develop, within 5 to 10 years, a synthetic biological agent to which no natural immunity exists.

1970 - Funding for the synthetic biological agent is obtained under H.R. 15090. The project, under the supervision of the CIA, is carried out by the Special Operations Division at Fort Detrick, the army's top secret biological weapons facility. Speculation is raised that molecular biology techniques are used to produce AIDS-like retroviruses.

1970 - United States intensifies its development of "ethnic weapons" (Military Review, Nov., 1970), designed to selectively target and eliminate specific ethnic groups who are susceptible due to genetic differences and variations in DNA.

1975 - The virus section of Fort Detrick's Center for Biological Warfare Research is renamed the Fredrick Cancer Research Facilities and placed under the supervision of the National Cancer Institute (NCI) . It is here that a special virus cancer program is initiated by the U.S. Navy, purportedly to develop cancer-causing viruses. It is also here that retrovirologists isolate a virus to which no immunity exists. It is later named HTLV (Human T-cell Leukemia Virus).

1977 - Senate hearings on Health and Scientific Research confirm that 239 populated areas had been contaminated with biological agents between 1949 and 1969. Some of the areas included San Francisco, Washington, D.C., Key West, Panama City, Minneapolis, and St. Louis.

1978 - Experimental Hepatitis B vaccine trials, conducted by the CDC, begin in New York, Los Angeles and San Francisco. Ads for research subjects specifically ask for promiscuous homosexual men.

1981 - First cases of AIDS are confirmed in homosexual men in New York, Los Angeles and San Francisco, triggering speculation that AIDS may have been introduced via the Hepatitis B vaccine.

1985 - According to the journal Science (227:173-177), HTLV and VISNA, a fatal sheep virus, are very similar, indicating a close taxonomic and evolutionary relationship.

1986 - According to the Proceedings of the National Academy of Sciences (83:4007-4011), HIV and VISNA are highly similar and share all structural elements, except for a small segment which is nearly identical to HTLV. This leads to speculation that HTLV and VISNA may have been linked to produce a new retrovirus to which no natural
immunity exists.

1986 - A report to Congress reveals that the U.S. Government's current generation of biological agents includes: modified viruses, naturally occurring toxins, and agents that are altered through genetic engineering to change immunological character and prevent treatment by all existing vaccines.

1987 - Department of Defense admits that, despite a treaty banning research and development of biological agents, it continues to operate research facilities at 127 facilities and universities
around the nation.

1990 - More than 1500 six-month old black and Hispanic babies in Los Angeles are given an "experimental" measles vaccine that had never been licensed for use in the United States. CDC later admits that parents were never informed that the vaccine being injected to their children was experimental.

1994 - With a technique called "gene tracking," Dr. Garth Nicolson at the MD Anderson Cancer Center in Houston, TX discovers that many returning Desert Storm veterans are infected with an altered strain of Mycoplasma incognitus, a microbe commonly used in the production
of biological weapons. Incorporated into its molecular structure is 40 percent of the HIV protein coat, indicating that it had been man-made.

1994 - Senator John D. Rockefeller issues a report revealing that for at least 50 years the Department of Defense has used hundreds of thousands of military personnel in human experiments and for intentional exposure to dangerous substances. Materials included
mustard and nerve gas, ionizing radiation, psychochemicals, hallucinogens, and drugs used during the Gulf War.

1995 - U.S. Government admits that it had offered Japanese war criminals and scientists who had performed human medical experiments salaries and immunity from prosecution in exchange for data on biological warfare research.

1995 - Dr. Garth Nicolson, uncovers evidence that the biological agents used during the Gulf War had been manufactured in Houston, TX and Boca Raton, Fl and tested on prisoners in the Texas Department of Corrections.

1996 - Department of Defense admits that Desert Storm soldiers were exposed to chemical agents.

1997 - Eighty-eight members of Congress sign a letter demanding an investigation into bioweapons use & Gulf War Syndrome.

Note: For more information on these important matters, see our two-page mind control summary at http://www.WantToKnow.info/mindcontrol or even better, the information-packed 10-page summary at http://www.WantToKnow.info/mindcontrol10pg. By informing you friends and colleagues of these little-reported facts, you can help to build the critical mass necessary to force the media to give adequate coverage and stop these abuses. Let us work towards ever greater transparency both in government and in our own personal lives.

Thanks for caring.

See our archive of revealing news articles at
http://www.WantToKnow.info/indexnewsarticles

September 19, 2007

Ebola virus was bungled in Wisconsin

Showing Lax Oversight

Can you say government biochemical research???!!!

RELATED RESOURCES:

Sources for this news release

More accident information:
Anthrax and Tularemia Bioweapons Bungling in Texas (18 Sep 2007)
Texas A&M More the Norm than the Exception (26 Jun 2007)
The Bird Flu Lab Accident that Officially Didn't Happen (26 Jan 2007)

Oversight Information:
Institutional Biosafety Committees: Biosafety Bites 2006/2007

The Sunshine Project
News Release
19 September 2007

Ebola Error in Wisconsin Shows Lax Federal Biodefense Oversight
Similar Violations May be Undetected Elsewhere

In 2005 and into the summer of 2006, researchers at the University of Wisconsin at Madison (UW) made and manipulated copies of the entire Ebola virus genome without proper safety precautions. Although federal safety rules required a maximum protection Biosafety Level Four (BSL-4) lab for the research, UW allowed it to proceed at the much less safe and secure BSL-3 level. The rules that UW broke are intended to ensure that agents that are easily transmissible and usually incurable don't escape maximum containment. They prohibit working at BSL-3 with Ebola (and similarly dangerous) virus material that has not been rendered irreversibly incapable of reproducing. UW does not have a BSL-4 lab suitable for handling Ebola virus, which is one of the most dangerous pathogens in the world.

Despite the contrary provisions of the NIH Guidelines for Research Involving Recombinant DNA Molecules, permission for UW scientist Yoshihiro Kawaoka to perform the Ebola genome work at BSL-3 was granted by the University of Wisconsin Institutional Biosafety Committee (IBC). This significant violation of NIH Guidelines was not detected in a timely manner by the National Institutes of Health (NIH) or, apparently, by the CDC Select Agent Program staff that inspect the Kawaoka lab.

Ebola virus was first recognized in 1976 in Africa. It is one of the more dangerous pathogens on earth. It is transmitted from person to person and causes a deadly hemorrhagic fever. Most people who contract Ebola quickly die from the disease. Its gruesome progression has provided horrific grist for innumerable popular books and movies, such as "The Hot Zone". An Ebola outbreak currently underway in the Democratic Republic of Congo has claimed an estimated 170 lives.

(A sources section a the bottom of this news release provides links to more information.)

KEEPING EBOLA IN THE BSL-4: The degree of danger posed by the work at UW, which involved manipulation of full-length Ebola cDNAs (see "The Science" below) is scientifically debatable. Some might argue the work was not terribly unsafe, because the Ebola constructs were not used together with two critical proteins whose presence would trigger growth of virulent virus. Others would argue that it was irresponsible to handle complete DNA copies of a virus as deadly as Ebola at less than BSL-4 when the copies were capable of producing virulent virus. From a security standpoint, it may also be argued that it is inadvisable to facilitate access to the Ebola virus by distributing the means to produce it (i.e. the cDNAs) to facilities other than BSL-4 labs, which are fewer and have the strongest security measures in place.

OVERSIGHT FAILURE: The research was not halted until Kawaoka remarkably repeatedly pushed for permission to lower it to biosafety level two (BSL-2), which is used for diseases that are comparatively mild and easy to treat. Kawaoka's persistence in requesting the even lower BSL-2 standard prompted a UW official to consult with the National Institutes of Health, whereupon it was determined that UW did not have appropriate facilities and should never have approved the studies at all.

But the organization that was funding the research, which explicitly included precisely the activity that violated NIH rules, was none other than NIH itself. "NIH disapproved its own project," says Sunshine Project Director Edward Hammond, "but it wasn't stopped because NIH's left hand knew what the right was doing, it was essentially by chance and long after the project started." Says Hammond, "After of years of studying NIH's toothless enforcement of its own Guidelines, it is dismaying but not surprising that NIH's biodefense program was funding work that violates NIH's safety rules. The Guidelines have been an unenforced afterthought for years."

There are several troubling questions remain:

1) Why did the Madison IBC approve the project in the first place?

2) Why doesn't the National Institutes of Health Office of Biotechnology Activities, which is supposed to oversee this work, have a system in place that detects such violations, especially when NIH is funding the work?

3) Why did the Centers for Disease Control apparently fail to identify the problem? The Kawaoka lab handles select agents and is thus subject to registry and inspection by CDC. Is not an inadequate lab experimenting with the complete means to produce Ebola something that CDC's Select Agent Program should identify and act upon?

Says Hammond, "NIH's Office of Biotechnology Activities has no idea what's going on in the labs it allegedly oversees. It is well-established that there is practically zero oversight NIH under the NIH Guidelines and common knowledge that there is never any penalty for disobeying them."

CELEBRITY STANDARDS? The Kawaoka Lab is known for work on the bleeding edge of virology. It is a world of dangerous experiments with dangerous diseases, such as infecting monkeys with deadly agents. Daring lab workers frequently deal with diseases like 1918 influenza and - by protocol - preemptively pop Tamiflu like it was breath mint. Engineering controls clearly don't seem to themselves inspire complete confidence. It is doubtful that many other virologists would gain institutional approval for some of the lab's practices or, for that matter, would be willing to routinely subject themselves to some of the lab's risks.

The lab is well funded with biodefense grants and is at once admired and controversial. In late 2004, UW and the University of Pittsburgh got into an unseemly bidding war over the scientist, offering up tens of millions of dollars in salaries, labs, people, and other public resources in packages more reminiscent of a MTV pop music star's concert rider than a college professor's salary contract.

"Pecking order means a lot in biology, in Madison and elsewhere, and Kawaoka is a big bird," says Hammond. The Sunshine Project would like to know if celebrity status caused UW to disregard the NIH Guidelines and lower safety and security standards: "If it had wanted to, was the IBC even realistically able to veto Kawaoka's research plans after the University had spent millions to keep him, blowing cash and political capital all the way to the governor's office? That these imbalanced situations exist at all is one good reason to make IBC compliance a matter of law instead of guideline."

SIMILAR RISK ELSEWHERE? In the course of researching this news release, the Sunshine Project identified a project at Tulane University in New Orleans, Louisiana that may also be handling complete cDNAs for BSL-4 agents at lesser safety levels. In the Tulane case, Ebola is again involved, along with Lassa virus, another hemorrhagic fever virus with African origins.

Documentation available from Tulane, however, is imprecise. Minutes from the Tulane IBC state that the Garry Lab will have Lassa and Ebola cDNAs and that the researcher "could replicate it [the virus] if he wanted to", suggesting complete cDNAs at another lab with no BSL-4 containment. In Tulane's case, the US Army is providing the cDNAs.

The Sunshine Project asked the Tulane researchers and their supervisors for clarification about the research six times. Tulane officials refused to respond at all. The Sunshine Project then asked the NIH Office of Biotechnology Activities about the possibly noncompliant research. NIH didn't reply to questions either.

THE SCIENCE: Some viruses including Ebola have genetic code that is composed of RNA, rather than the DNA molecule that is the basis of heredity in higher organisms. In higher organisms, information from DNA is translated into RNA that then serves as a "messenger", directing what other parts of living cells do. RNA viruses lack the tools to copy themselves independently, and instead reproduce by hijacking normal DNA-RNA translation processes in cells.

For some RNA viruses, such as influenza, scientists (including the Kawaoka Lab) have developed so-called "reverse genetics" systems that take scientific advantage of how RNA viruses multiply. They have constructed DNA copies of the virus. When the DNA copies (called cDNAs, or "complimentary DNA") are allowed to reproduce under appropriate conditions, they will churn out RNA that is assembled into live virus. The systems allow scientists to "edit" the RNA virus by tweaking the cDNA that produces it. The effects of such genetic tweaks are not necessarily predictable, and may change the virus in ways that make it more or less dangerous. Viruses produced by reverse genetics may be used for research and vaccine purposes.


SOURCES:

IBC Minutes of both the University of Wisconsin at Madison and Tulane University can be downloaded from the Sunshine Project IBC Minutes archive at:
http://www.sunshine-project.org/ibc/archive.html

E-mail between Bruce Whitney of NIH OBA and Jan Klein of UW Madison, July and October 2006 (obtained under the Wisconsin Public Records Law):
http://www.sunshine-project.org/publications/pr/support/UWcDNAs.pdf

Molecular Basis for Ebola Virus Pathogenicity, NIAID grant to UW Madison's Yoshihiro Kawaoka, #1R01AI055519
Recombinant antigen assays for Lassa and other arenaviru [sic], NIAID grant to Tulane's Robert Garry, #1UC1AI067188
Summarie accessible here (search on the researcher's last name, with a relevant keyword, such as "Ebola"):
http://www.sunshine-project.org/crisper/crisper_basic_search.php

"Flight Lessons", an article from the University of Wisconsin Alumni Magazine concerning UW and Pitt's competition:
http://www.uwalumni.com/home/onwisconsin/archives/winter06/Yoshi.aspx

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